NEW EQUIPMENT TO IMPROVE RESEARCH ON THROMBOSIS

THE PLATELETS RESEARCH LAB ACQUIRED A MICROSCOPE OF UNIQUE CHARACTERISTICS IN CHILE. TOGETHER WITH THE CPF, IT WILL NOW START CLINICAL STUDIES IN HUMANS.



October 14, 2016

A key piece in the development of the research done by the Platelets Research Laboratory from the Department of Health Sciences is the new equipment installed in this complex that will advance the knowledge on cardiovascular diseases and its forms of prevention.

The lab belongs to the Department of Clinical Biochemistry and Immunohematology has been studying the participation of platelets in the atherothrombotic process, that is to say, the generation of thrombi in the arteries causing cardiovascular diseases, for more than five years. In this context, biological activities have been evaluated that prevent cardiovascular disease -- antithrombotic and antiplatelet- from the extracts of fruits and vegetables of bioactive natural compounds and synthesis.

The director of the aforementioned laboratory, Ivan Palomo, said that, until now, the action of compounds derived mainly from tomato residues, or tomasa, - skin and seeds that are wasted in the industrial processes - has been researched, and the studies have also included strawberry, blueberry and asparagus.

He explained that it will now be possible to consolidate this research with support of the intravital fluorescence microscope – an Axio Examiner Z1, Carl Zeiss- awarded in the IV Fondequip CONICYT Contest.

The coordinator of this project, Eduardo Fuentes, indicated that this is an equipment of unique characteristics in Chile and that will expand and deepen the knowledge around the generation of thrombosis and help to combat a problem that affects a large part of the national population and the world, as are the cardiovascular diseases. The academic furthermore explained that this equipment, together with others obtained by Fondecyt Projects, will be a key piece in the development of the research being conducted by the Platelets Research Laboratory.

In this regard, Ivan Palomo said that experiments have been carried out in vitro and in vivo and currently, together with the Center of Processed Foods (CPF), the clinical study in humans begins, with a participation of 90 people.
The research has generated several publications and at the end of the year the researchers estimate that they will add another product of this type, as a result from the studies. "We believe that with the new equipment we will take a significant leap forward in this work," he commented, together with stressing also the participation of Professor Marcelo Alarcón and the contribution of the theses from doctoral and master’s degree students.

According to Professor Palomo, the microscope purchased has an approximate cost of 200 million pesos (US$ 307 000 approx.), with about 20% funded the University and the rest came from Fondequip.



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